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The U.S. Nuclear Regulatory Commission is in the process of rescinding or revising guidance and policies posted on this webpage in accordance with Executive Order 14151 Ending Radical and Wasteful Government DEI Programs and Preferencing, and Executive Order 14168 Defending Women From Gender Ideology Extremism and Restoring Biological Truth to the Federal Government. In the interim, any previously issued diversity, equity, inclusion, or gender-related guidance on this webpage should be considered rescinded that is inconsistent with these Executive Orders.

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Information Notices of Interest to Medical Use Licensees

The following notices are listed by year:

2000s: 2024 2023 2021 2019 2017 2016 2014 2013
2012 2011 2010 2009 2008 2007 2006 2005
2004 2003 2002 2001 2000  
1900s: 1999 1998 1986  

 

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2024
IN-2024-04 08/09/2024 Recent Medical Events Involving Administrative of Therapeutic Radiopharmaceuticals
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2023
IN-2023-05 11/30/2023 Discontinuation of the U.S. NRC’s Recognition of the American Board of Radiology’s Certification Process
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2021
IN-2021-02 08/04/2021 Recent Issues Associated with Monitoring Occupational Exposure to Radiation from Licensed and Unlicensed Radiation Sources
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2019
IN-2019-12 12/31/2019 Recent Reported Medical Events Involving the Administration of Yttrium-90 Microspheres for Therapeutic Medical Procedures
IN-2019-11 12/23/2019 Strontium-82/Rubidium-82 Generator Elution Events and Issues
IN-2019-07 08/26/2019 Methods to prevent medical events
IN-2019-06 08/26/2019 Patient skin contamination events Associated with I-131 Metaiodobenzylguanidine during Neuroblastoma treatments
IN-2019-04 08/14/2019 Effective Cyber Security Practices to Protect Digital Assets of Byproduct Materials Licensees
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2017
IN-2017-02 05/17/2017 Best Practice Concepts for Patient Release
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2016
IN-2016-03 01/12/2016 Revision to the National Institute of Standards and Technology Standard for Radium-223 and Impact on Dose Calibration for the Medical Use of Radium-223 Dichloride
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2014
IN-2014-05 05/12/2014 Verifying Appropriate Dosimetry Evaluation
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2013
IN-2013-16 08/12/2013 Importance of Verification of Treatment Parameters for High Dose-Rate Remote Afterloader Administrations
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2012
IN-2012-08 04/10/2012 High Dose-Rate Remote Afterloader (HDR) Physical Presence Requirements
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2011
IN-2011-11 04/27/2011 Reporting Requirement For Heat And Smoke Detector Failures In 10 CFR Part 36 Irradiators
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2010
IN-2010-24 11/19/2010 Notice of Possible Source Leakage During Non-Routine Maintenance on a Gammacell 40 Irradiator
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2009
IN-2009-30 11/06/2009 Findings From The NRC Initiative To Assess Materials Licensees' Compliance With The NRC Decommissioning Requirements
IN-2009-27 11/13/2009 Revised International Nuclear And Radiological Event Scale User's Manual
IN-2009-17 08/28/2009 Reportable Medical Events Involving Treatment Delivery Errors Caused By Confusion Of Units For The Specification Of Brachytherapy Sources
IN-2009-15 08/28/2009 Varian Medical Systems Varisource High Dose-Rate Remote Afterloader Events: Source Retraction Problems
IN-2009-07 03/30/2009 Withholding of Propriety Information from Public Disclosure
IN-2009-05 02/03/2009 Contamination Events Resulting From Damage To Sealed Radioactive Sources During Gauge Dismantlement And Non-Routine Maintenance Operations
IN-2009-01 01/22/2009 National Response Framework
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2008
IN-2008-22 01/12/2009 Molybdenum-90 Breakthrough in Molybdenum-99/Technetium-99m Generators
IN-2008-03 05/16/2008 Precautions to take before Sharing Sensitive Security-Related Information
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2007
IN-2007-38 12/14/2007 Ensuring Complete and Accurate Information in the Documentation of Training and Experience for Individuals Seeking Approval as Medical Authorized Users
IN-2007-35 10/17/2007 Varian Medical Systems Varisource HDR Events: Iridium-192 Source Pulled From Shielded Position
IN-2007-25 07/19/2007 Suggestion from the Advisory Committee on the Medical Use of Isotopes for Consideration to Improve Compliance With Sodium Iodide I-131 Written Directive Requirements in 10 CFR 35.40 and Supervision Requirements in 10 CFR 35.27
IN-2007-16 05/02/2007 Common Violations of the Increased Controls Requirements and Related Guidance Documents
IN-2007-10 03/05/2007 Yttrium-90 Therashperes and SIRSpheres Impurities
IN-2007-08 02/28/2007 Potential vulnerabilities of time-reliant computer-based systems due to change in daylight saving time dates
IN-2007-03 02/02/2007 Reportable Medical Events Involving Patients Receiving Dosages of Sodium Iodide Iodine-131 Less Than the Prescribed Dosage Because of Capsules Remaining in Vials After Administration
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2006
IN-2006-12 07/06/2006 Exercising Due Diligence when Transferring Radioactive Materials
IN-2006-11 06/12/2006 Applicability of Patient Intervention in Determining Medical Events for Gamma Stereotactic Radiosurgery and Other Therapy Procedures
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2005
IN-2005-27 10/07/2005 Low-Dose-Rate Manual Brachytherapy – Equipment-Related Medical Events
IN-2005-17 06/23/2005 Manual Brachytherapy Source Jamming
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2004
IN-2004-02 02/05/2004 Strontium-90 Eye Applicators: New Calibration Values and Use
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2003
IN-2003-22 12/09/2003 Heightened Awareness for Patients Containing Detectable Amounts of Radiation from Medical Administrations
IN-2003-21 11/24/2003 High-Dose-Rate-Remote-Afterloader Equipment Failure
IN-2003-12 08/22/2003 Problems Involved in Monitoring Dose to the Hands Resulting from the Handling of Radiopharmaceuticals
IN-2003-09 07/16/2003 Source Positioning Errors and System Malfunctions During Administration of Intravascular Brachytherapy
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2002
IN-2002-36 12/27/2002 Incomplete of Inaccurate Information Provided to the Licensee And/or NRC by Any Contractor or Subcontractor Employee
IN-2002-33 11/22/2002 Notification of Permanent Injunction Against Neutron Products Incorporated of Dickerson, Maryland
IN-2002-28 09/27/2002 Appointment of Radiation Safety Officers and Authorized Users Under 10 CFR Part 35
IN-2002-23 07/16/2002 Unauthorized Administration of Byproduct Material for Medical Use
IN-2002-23s1 03/21/2003 Unauthorized Administration of Byproduct Material for Medical Use
IN-2002-19 06/14/2002 Medical Misadministrations Caused by Failure to Properly Perform Tests on Dose Calibrators for Beta -and Low-Energy Photon-Emitting Radionuclides
IN-2002-17 05/30/2002 Medical Use of Strontium-90 Eye Applicators: New Requirements for Calibration and Decay Correction
IN-2002-16 05/01/2002 Intravascular Brachytherapy Misadministrations
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2001
IN-2001-08s1 06/06/2001 Update on the Investigation of Patient Deaths in Panama, Following Radiation Therapy Overexposures
IN-2001-08 06/01/2001 Treatment Planning System Errors Result in Deaths of Overseas Radiation Therapy Patients
IN-2001-01 03/26/2001 The Importance of Accurate Inventory Controls to Prevent the Unauthorized Possession of Radioactive Material
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2000
IN-2000-22 12/18/2000 Medical Misadministrations Caused by Human Errors Involving Gamma Stereotactic Radiosurgery (Gamma Knife)
IN-2000-19 12/05/2000 Implementation of Human Use Research Protocols Involving U.S. Nuclear Regulatory Commission Regulated Materials
IN-2000-16 10/05/2000 Potential Hazards Due to Volatilization of Radionuclides
IN-2000-10 07/18/2000 Recent Events Resulting in Extremity Exposures Exceeding Regulatory Limits
IN-2000-05 03/06/2000 Recent Medical Misadministrations Resulting from Inattention to Detail
IN-2000-04 02/25/2000 Enforcement Sanctions for Deliberate Violations of NRC Employee Protection Requirements
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1999
IN-99-27 09/02/1999 Malfunction of Source Retraction Mechanism in Cobalt-60 Teletherapy Treatment Units
IN-99-23 7/06/1999 Safety Concerns Related to Repeated Control Unit Failures of the Nucletron Classic Model High-Dose-Rate Remote Afterloading Brachytherapy Devices
IN-99-11 4/16/1999 Incidents Involving the Use of Radioactive Iodine-131
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1998
IN-98-12 4/03/1998 Licensees' Responsibilities Regarding Reporting and Follow-Up Requirements for Nuclear-Powered Pacemakers
IN-98-10 3/09/1998 Probable Misadministrations Occurring During Intravascular Brachytherapy with the Novoste Beta-Cath System
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1986
IN-86-59 07/14/1986 Increased Monitoring of Certain Patients with Implanted Coratomic, Inc, Model C-100 and C-101 Nuclear-Powered Cardiac Pacemakers
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Page Last Reviewed/Updated Monday, March 24, 2025