United States Nuclear Regulatory Commission - Protecting People and the Environment

Monica Regalbuto

Dr. Regalbuto is currently the Deputy Assistant Secretary for Fuel Cycle Technologies with the Department of Energy’s Office of Nuclear Energy, whose mission promotes nuclear power as a resource capable of meeting the Nation's energy, environmental and national security needs. She previously served as a Senior Program Manager with the Office of Waste Processing with the Department of Energy’s Office of Environmental Management, supporting technical risk reduction and uncertainty in the Department’s clean-up programs. From 2003 to 2008, Dr. Regalbuto served as the head of the Process Chemistry and Engineering Department in Argonne’s Chemical Sciences and Engineering Division and managed a group of 30 researchers. Dr. Regalbuto has been a key contributor to the development of nuclear fuel cycle technologies, where she combines her experience in separations, computer simulations and proliferation resistance. She was part of the Massachusetts Institute of Technology 2010 Fuel Cycle Study Team. Dr. Regalbuto has contributed to the development of innovative energy technologies throughout her professional career. As a researcher at Argonne National Laboratory, she has made key contributions to nuclear fuel cycle technology, beginning with the TRUEX process for removing transuranic elements from aqueous acidic solutions such as those found at DOE waste sites throughout the United States followed by the development of advanced separations processes as alternatives for recycling spent fuel. She led the development of AMUSE, a computer model used by researchers to optimize processes for separating dissolved spent nuclear fuel. Under Dr. Regalbuto’s leadership, Argonne conducted highly successful process demonstrations, the CSSX process, a process for separating cesium-137 from high-level radioactive waste at DOE’s Savannah River site and the UREX+ processes, a suite of solvent extraction processes for the recovery of actinides and fission products. In support of her professional growth, Dr. Regalbuto joined Amoco Oil Company in December 1996 to fulfill her desire to apply her research and development expertise in an industrial setting. As a member of Amoco’s Hydroprocessing Team she provided key technical support to several refineries. Subsequently at Amoco, she was tapped to participate in a newly formed team to develop and evaluate alternative technologies for lowering the sulfur levels of gasoline. Dr. Regalbuto has authored multiple journal articles, reports, and presentations and holds six patents.


  • Outstanding Engineering Achievement by the Illinois Engineering Council, 2005
  • Jane Oestmann Professional Women’s Achievement Award, American Nuclear Society, 2007
  • Professional Achievement Award, Hispanic Engineer National Achievement Award Corporation (HENAAC), 2007
  • 25 Outstanding Hispanic Women in Business, HispanicBusiness.com, 2009
  • 2010 Powerful Hispanics in Energy, Hispanic Engineer & Information Technology Magazine, 2010

Professional Memberships

  • American Nuclear Society
  • American Institute of Chemical Engineers
  • American Chemical Society
  • Society of Women Engineers
  • Sigma Xi Scientific Research Society


  • 1988 Ph. D., Ch. E., University of Notre Dame
  • 1986 MS., Ch. E., University of Notre Dame
  • 1983 BS., Ch. E., Instituto Tecnologico y de Estudios Superiores de Monterrey (ITESM)


  • "The Future of The Nuclear Fuel Cycle," An Interdisciplinary MIT Study, September 2010, http://web.mit.edu/mitei/docs/spotlights/nuclear-fuel-cycle.pdf (coauthor)

  • "Advanced Separation Techniques for Nuclear Fuel Reprocessing and Radioactive Waste Treatment" , Chapter 11: “ Alternative Separation/Extraction: UREX+ Processes for Actinide and Targeted Fission Product Recovery”, Woodhead Publishing Limited Abington Hall, Granta Park Cambridge, CB21 6AH, UK, 2011, in press (author)

  • “External Technical Review for Evaluation of System Level Modeling and Simulation Tools in Support of Hanford Site Liquid Waste Process”, DOE-EM, September 2009, http://www.em.doe.gov/EM20Pages/TankWasteReferencePage.aspx#ETR (lead author)

  • “External Technical Review for Evaluation of System Level Modeling and Simulation Tools in Support of Savannah River Site Liquid Waste Process”, DOE-EM, June 2009, http://www.em.doe.gov/EM20Pages/TankWasteReferencePage.aspx#ETR (lead author)

  • “Preparation of Components for Refinery Blending of Transportation Fuels”, U.S. Patent 6,827,845, December 7, 2004 (co-inventor)
Page Last Reviewed/Updated Thursday, March 29, 2012