United States Nuclear Regulatory Commission - Protecting People and the Environment

Integrated Safety Analysis Guidance Document (NUREG-1513)

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Publication Information

Manuscript Completed: May 2001
Date Published:
May 2001

Prepared by:
R.I. Milstein

Division of Fuel Cycle Safety and Safeguards
Office of Nuclear Material Safety and Safeguards
U.S. Nuclear Regulatory Commission
Washington, DC 20555-0001

Availability Notice


On September 18, 2000, the U. S. Nuclear Regulatory Commission published a final rule, 10 CFR Part 70, for licensing the use of special nuclear material. In this rule, NRC included a requirement that certain licensee/applicants subject to 10 CFR 70 conduct an integrated safety analysis (ISA). The purpose of this document is to provide general guidance to NRC fuel cycle licensee/applicants on how to perform an integrated safety analysis (ISA) and document the results. In particular, the document defines an ISA, identifies its role in a facility's safety program, identifies and describes several generally accepted ISA methods, and provides guidance in choosing a method.

The approaches and methods described in this document are not a substitute for NRC regulations, and compliance is not required. This document does not itself impose regulatory requirements, nor does it address acceptance criteria for an ISA. As discussed in Section 1.3, "Purpose of Document," acceptance criteria for ISA are addressed in the "Standard Review Plan for the Review of a License Application for a Fuel Cycle Facility," draft NUREG-1520.

Page Last Reviewed/Updated Tuesday, May 31, 2016